Plasma-Derived Medicinal Products (PDMPs)

The Healthonauts bring a decade of hands-on experience across the plasma value chain, supporting companies operating in the complex and highly regulated PDMP environment.

We understand the operational realities of plasma, from source plasma and fractionation through to supply chain resilience, regulatory compliance and market delivery. Our experience spans the full lifecycle, including commercial strategy, market entry, product launch and long-term growth.

PDMP markets require careful balancing of supply security, tender strategy, pricing discipline and stakeholder management. We support clients in designing and executing robust tender and contracting strategies, aligned with national procurement frameworks and payer expectations, while protecting sustainable value.

We also advise on the selection, set-up and management of distribution partners, ensuring clear governance, aligned incentives and effective market coverage. Where appropriate, we support transitions between distribution and direct models.

Our work consistently focuses on building scalable, resilient commercial models that deliver reliable access for patients and steady, sustainable sales growth over time.

We also support the procurement of PDMPs on an ad hoc basis to fill supply chain needs for individual markets including IVIg

PDMP expertise includes

• Plasma operations and end-to-end supply chain understanding

• Go-to-market and commercial strategy

• Product launch planning and execution

• Tender and contracting strategy

• Distributor selection, governance and performance management

• Sales growth and lifecycle optimisation

Example

David Lewis supported the development, and led the UK and EU launch of an ultra-orphan PDMP. He established the controlled EU supply chain, navigated market access and procurement processes in direct affiliate markets and in partnership with distributors (achieving prices reflecting the innovation, and any times higher than the prevailing technology) and was able to grow sales at a controlled pace in line with available production.

More recently, David has supported the identification PDMP supplies to overcome market shortages.